Storing Temp files from Win10 is not a problem, I use a 3 GB RamDisk for this (from 12GB RAM avail). But since the Anniversary Update (winver 1607), there seems to be something changed in the system routines. You should have UNCHECKED
the option "Hard Drive Emulation". With this option enabled I found out, that MS Office will fail to write files in the RamDisk and OpenOffice/LibreOffice will fail writing any files everywhere, because it cannot write to the temp folder (it creates a backup file there) for a reason I cannot understand since normal file operations in such a RamDisk are no problem. If you disable the Emulation, everything is fine.